An Evolutionary Model-Based Algorithm for Accurate Phylogenetic Breakpoint Mapping and Subtype Prediction in HIV-1.
Sergei L. Kosakovsky PondDavid PosadaEric StawiskiColombe ChappeyArt F. Y. PoonGareth HughesEsther FearnhillMike B. GravenorAndrew J. Leigh BrownSimon D. W. FrostPublished in: PLoS Comput. Biol. (2009)
Keyphrases
- detection algorithm
- computational complexity
- np hard
- learning algorithm
- mapping function
- tree structure
- simulated annealing
- preprocessing
- k means
- prediction algorithm
- prediction error
- dynamic programming
- improved algorithm
- convergence rate
- high accuracy
- computationally efficient
- segmentation algorithm
- times faster
- expectation maximization
- worst case
- computational cost
- experimental evaluation
- data structure
- search space
- objective function
- prediction accuracy
- decision trees
- classification algorithm
- matching algorithm
- prediction model
- cost function
- significant improvement
- neural network