Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks.
Daniel C. KirouacJulio Saez-RodriguezJennifer SwantekJohn M. BurkeDouglas A. LauffenburgerPeter K. SorgerPublished in: BMC Syst. Biol. (2012)
Keyphrases
- signal transduction
- protein protein interactions
- protein interaction
- biological systems
- biological networks
- protein interaction networks
- functional modules
- cellular processes
- network analysis
- ppi networks
- complex systems
- biological processes
- protein complexes
- network topology
- systems biology
- high throughput
- network structure
- protein function
- computational methods
- biomedical literature
- high precision
- biologically inspired
- gene ontology
- biological data
- signaling pathways
- structural properties
- mathematical modeling
- gene networks
- computational approaches
- social network analysis
- data sets
- community structure
- community detection
- protein function prediction