Giorgio Colombo

Publication Activity (10 Years)

Years Active: 2001-2023
Publications (10 Years): 11

Top Topics

Computational Model

Computationally Tractable

Protein Functional

Top Venues

J. Chem. Inf. Model.

J. Comput. Aided Mol. Des.

PLoS Comput. Biol.

Publications

Luca Torielli, Stefano A. Serapian, Lara Mussolin, Elisabetta Moroni, Giorgio Colombo
Integrating Protein Interaction Surface Prediction with a Fragment-Based Drug Design: Automatic Design of New Leads with Fragments on Energy Surfaces. J. Chem. Inf. Model. 63 (1) (2023)
Alice Triveri, Stefano A. Serapian, Filippo Marchetti, Filippo Doria, Silvia Pavoni, Fabrizio Cinquini, Elisabetta Moroni, Andrea Rasola, Francesco Frigerio, Giorgio Colombo
SARS-CoV-2 Spike Protein Mutations and Escape from Antibodies: A Computational Model of Epitope Loss in Variants of Concern. J. Chem. Inf. Model. 61 (9) (2021)
Silvia Rinaldi, Giorgio Colombo, Antonella Paladino
Mechanistic Model for the Hsp90-Driven Opening of Human Argonaute. J. Chem. Inf. Model. 60 (3) (2020)
Marco Montefiori, Simona Pilotto, Chiara Marabelli, Elisabetta Moroni, Mariarosaria Ferraro, Stefano A. Serapian, Andrea Mattevi, Giorgio Colombo
Impact of Mutations on NPAC Structural Dynamics: Mechanistic Insights from MD Simulations. J. Chem. Inf. Model. 59 (9) (2019)
Emanuele Breuza, Giorgio Colombo, Daniele Gregori, Filippo Marchetti
Molecular Dynamics Performance Evaluation with Modern Computer Architecture. NUMTA (2) (2019)
Riccardo Capelli, Filippo Marchetti, Guido Tiana, Giorgio Colombo
SAGE: A Fast Computational Tool for Linear Epitope Grafting onto a Foreign Protein Scaffold. J. Chem. Inf. Model. 57 (1) (2017)
Antonella Paladino, Monica Civera, Laura Belvisi, Giorgio Colombo
High Affinity vs. Native Fibronectin in the Modulation of αvβ3 Integrin Conformational Dynamics: Insights from Computational Analyses and Implications for Molecular Design. PLoS Comput. Biol. 13 (1) (2017)
Silvia Rinaldi, Alessandro Gori, Celeste Annovazzi, Erica E. Ferrandi, Daniela Monti, Giorgio Colombo
Unraveling Energy and Dynamics Determinants to Interpret Protein Functional Plasticity: The Limonene-1, 2-epoxide-hydrolase Case Study. J. Chem. Inf. Model. 57 (4) (2017)
Jacopo Sgrignani, Filomena De Luca, Hayarpi Torosyan, Jean-Denis Docquier, Da Duan, Beatrice Novati, Fabio Prati, Giorgio Colombo, Giovanni Grazioso
Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors. J. Comput. Aided Mol. Des. 30 (10) (2016)
Jacopo Sgrignani, Beatrice Novati, Giorgio Colombo, Giovanni Grazioso
Covalent docking of selected boron-based serine beta-lactamase inhibitors. J. Comput. Aided Mol. Des. 29 (5) (2015)
Antonella Paladino, Giulia Morra, Giorgio Colombo
Structural Stability and Flexibility Direct the Selection of Activating Mutations in Epidermal Growth Factor Receptor Kinase. J. Chem. Inf. Model. 55 (7) (2015)
Elisabetta Moroni, Huiping Zhao, Brian S. J. Blagg, Giorgio Colombo
Exploiting Conformational Dynamics in Drug Discovery: Design of C-Terminal Inhibitors of Hsp90 with Improved Activities. J. Chem. Inf. Model. 54 (1) (2014)
Jacopo Sgrignani, Marta Bon, Giorgio Colombo, Alessandra Magistrato
Computational Approaches Elucidate the Allosteric Mechanism of Human Aromatase Inhibition: A Novel Possible Route to Small-Molecule Regulation of CYP450s Activities? J. Chem. Inf. Model. 54 (10) (2014)
Dario Corrada, Giorgio Colombo
Energetic and Dynamic Aspects of the Affinity Maturation Process: Characterizing Improved Variants from the Bevacizumab Antibody with Molecular Simulations. J. Chem. Inf. Model. 53 (11) (2013)
Giulia Morra, Raffaello Potestio, Cristian Micheletti, Giorgio Colombo
Corresponding Functional Dynamics across the Hsp90 Chaperone Family: Insights from a Multiscale Analysis of MD Simulations. PLoS Comput. Biol. 8 (3) (2012)
Federica Chiappori, Ivan Merelli, Giorgio Colombo, Luciano Milanesi, Giulia Morra
Molecular Mechanism of Allosteric Communication in Hsp70 Revealed by Molecular Dynamics Simulations. PLoS Comput. Biol. 8 (12) (2012)
Jessica Nasica-Labouze, Massimiliano Meli, Philippe Derreumaux, Giorgio Colombo, Normand Mousseau
A Multiscale Approach to Characterize the Early Aggregation Steps of the Amyloid-Forming Peptide GNNQQNY from the Yeast Prion Sup-35. PLoS Comput. Biol. 7 (5) (2011)
Giulia Morra, Gennady Verkhivker, Giorgio Colombo
Modeling Signal Propagation Mechanisms and Ligand-Based Conformational Dynamics of the Hsp90 Molecular Chaperone Full-Length Dimer. PLoS Comput. Biol. 5 (3) (2009)
Luca Monticelli, Eric J. Sorin, D. Peter Tieleman, Vijay S. Pande, Giorgio Colombo
Molecular simulation of multistate peptide dynamics: A comparison between microsecond timescale sampling and multiple shorter trajectories. J. Comput. Chem. 29 (11) (2008)
Andrea Bazzoli, Giorgio Colombo, Andrea Tettamanzi
Ab initio protein structure prediction with a dipeptide-assembly evolutionary algorithm. GECCO (2007)
Federico Fogolari, Silvio C. E. Tosatto, Giorgio Colombo
A decoy set for the thermostable subdomain from chicken villin headpiece, comparison of different free energy estimators. BMC Bioinform. 6 (2005)
Anna Bernardi, Marta Galgano, Laura Belvisi, Giorgio Colombo
Simulation of carbohydrate-protein interactions: Computer-aided design of a second generation GM1 mimic. J. Comput. Aided Mol. Des. 15 (2) (2001)