George M. Spyrou

Publication Activity (10 Years)

Years Active: 2006-2023
Publications (10 Years): 22

Top Topics

Data Integration

Clustered Microcalcifications

Top Venues

Briefings Bioinform.

IEEE ACM Trans. Comput. Biol. Bioinform.

Publications

George Minadakis, Marios Tomazou, Nikolas Dietis, George M. Spyrou
Vir2Drug: a drug repurposing framework based on protein similarities between pathogens. Briefings Bioinform. 24 (1) (2023)
Marios Tomazou, Marilena M. Bourdakou, George Minadakis, Margarita Zachariou, Anastasis Oulas, Evangelos Karatzas, Eleni M. Loizidou, Andrea C. Kakouri, Christiana C. Christodoulou, Kyriaki Savva, Maria Zanti, Anna Onisiforou, Sotiroula Afxenti, Jan Richter, Christina G. Christodoulou, Theodoros C. Kyprianou, George Kolios, Nikolas Dietis, George M. Spyrou
Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19. Briefings Bioinform. 22 (6) (2021)
Emmanouil K. Ikonomakis, Marilena M. Bourdakou, George Kolios, Michael N. Vrahatis, George M. Spyrou
Computational insights on the molecular mechanisms across breast cancer progression combining gene differential expression and co-expression. BHI (2021)
Maria Zanti, Kyriaki Michailidou, Maria Loizidou, Christina Machattou, Panagiota Pirpa, Kyproula Christodoulou, George M. Spyrou, Kyriacos Kyriacou, Andreas Hadjisavvas
Performance evaluation of pipelines for mapping, variant calling and interval padding, for the analysis of NGS germline panels. BMC Bioinform. 22 (1) (2021)
Anna Onisiforou, George M. Spyrou
Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches. Briefings Bioinform. 22 (6) (2021)
Evangelos Karatzas, Juan Eiros Zamora, Emmanouil Athanasiadis, Dimitris Dellis, Zoe Cournia, George M. Spyrou
ChemBioServer 2.0: an advanced web server for filtering, clustering and networking of chemical compounds facilitating both drug discovery and repurposing. Bioinform. 36 (8) (2020)
Evangelos Karatzas, Margarita Zachariou, Marilena M. Bourdakou, George Minadakis, Anastasis Oulas, George Kolios, Alex Delis, George M. Spyrou
PathWalks: identifying pathway communities using a disease-related map of integrated information. Bioinform. 36 (13) (2020)
Nikolas Dovrolis, George Kolios, George M. Spyrou, Ioanna Maroulakou
Computational profiling of the gut-brain axis: microflora dysbiosis insights to neurological disorders. Briefings Bioinform. 20 (3) (2019)
Anastasis Oulas, George Minadakis, Margarita Zachariou, Kleitos Sokratous, Marilena M. Bourdakou, George M. Spyrou
Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches. Briefings Bioinform. 20 (3) (2019)
Andrea C. Kakouri, Christiana C. Christodoulou, Margarita Zachariou, Anastasis Oulas, George Minadakis, Christiana A. Demetriou, Christina Votsi, Eleni Zamba-Papanicolaou, Kyproula Christodoulou, George M. Spyrou
Revealing Clusters of Connected Pathways Through Multisource Data Integration in Huntington's Disease and Spastic Ataxia. IEEE J. Biomed. Health Informatics 23 (1) (2019)
Maria Zanti, Maria Loizidou, Margarita Zachariou, Kyriaki Michailidou, Kyriacos C. Kyriacou, Andreas Hadjisavvas, George M. Spyrou
In Silico Assessment of the Structural, Functional and Stability Impact of a Nonsense PRF1 Mutation with Uncertain Clinical Significance; Identified in 2 Unrelated Cypriot Triple-Negative Breast Cancer Patients. BIBE (2019)
Andrea C. Kakouri, Christina Votsi, Marios Tomazou, Kyproula Christodoulou, George M. Spyrou
The Effect of a Spastic Ataxia Associated GBA2 Mutation on Protein-Protein Interactions and Pathways. BIBE (2019)
Emmanouil K. Ikonomakis, George M. Spyrou, Michael N. Vrahatis
Content driven clustering algorithm combining density and distance functions. Pattern Recognit. 87 (2019)
Christiana C. Christodoulou, George Minadakis, Christiana Demetriou, Eleni Zamba-Papanicolaou, George M. Spyrou
Computational Identification of Metabolites for Pathways Related to Huntington's Disease. BIBE (2019)
Evangelos Karatzas, Alex Delis, George Kolios, George M. Spyrou
Exploring Fibrotic Disease Networks to Identify Common Molecular Mechanisms with IPF. BIBE (2019)
George M. Tzanoukos, Pavlos Kafouris, Alexandros Georgakopoulos, Anastasios Gaitanis, Dimitris Maroulis, Sofia Chatziioannou, George M. Spyrou
Design and Initial Implementation of a Computer Aided Diagnosis System for PET/CT Solitary Pulmonary Nodule Risk Estimation. BIBE (2019)
George Minadakis, Margarita Zachariou, Anastasis Oulas, George M. Spyrou
PathwayConnector: finding complementary pathways to enhance functional analysis. Bioinform. 35 (5) (2019)
Marilena M. Bourdakou, George M. Spyrou
Informed walks: whispering hints to gene hunters inside networks' jungle. BMC Syst. Biol. 11 (1) (2017)
Emmanouil Athanasiadis, Marilena M. Bourdakou, George M. Spyrou
D-Map: Random Walking on Gene Network Inference Maps Towards differential Avenue Discovery. IEEE ACM Trans. Comput. Biol. Bioinform. 14 (2) (2017)
Nicholas E. Protonotarios, George M. Spyrou, George A. Kastis
Automatic cumulative sums contour detection of FBP-reconstructed multi-object nuclear medicine images. Comput. Biol. Medicine 85 (2017)
George M. Tzanoukos, Erast Athanasiadis, Anastasios Gaitanis, Alexandros Georgakopoulos, Achilleas Chatziioannou, Sofia Chatziioannou, George M. Spyrou
SPNsim: A database of simulated solitary pulmonary nodule PET/CT images facilitating computer aided diagnosis. J. Biomed. Informatics 63 (2016)
John C. Siavelis, Marilena M. Bourdakou, Emmanouil I. Athanasiadis, George M. Spyrou, Konstantina S. Nikita
Bioinformatics methods in drug repurposing for Alzheimer's disease. Briefings Bioinform. 17 (2) (2016)
Argiris Sakellariou, George M. Spyrou
mAPKL: R/ Bioconductor package for detecting gene exemplars and revealing their characteristics. BMC Bioinform. 16 (2015)
Stergiani V. Eleftheriou, Marilena M. Bourdakou, Emmanouil I. Athanasiadis, George M. Spyrou
GeneStoryTeller: a mobile app for quick and comprehensive information retrieval of human genes. Database J. Biol. Databases Curation 2015 (2015)
Emmanouil I. Athanasiadis, Marilena M. Bourdakou, George M. Spyrou
ZoomOut: Analyzing Multiple Networks as Single Nodes. IEEE ACM Trans. Comput. Biol. Bioinform. 12 (5) (2015)
Ioannis Andreadis, George M. Spyrou, Konstantina S. Nikita
A CAD$_{\bf x}$ Scheme for Mammography Empowered With Topological Information From Clustered Microcalcifications' Atlases. IEEE J. Biomed. Health Informatics 19 (1) (2015)
Emmanouil Athanasiadis, Kyriaki Antonopoulou, Foteini Chatzinasiou, Christina M. Lill, Marilena M. Bourdakou, Argiris Sakellariou, Katerina Kypreou, Irene Stefanaki, Evangelos Evangelou, John P. A. Ioannidis, Lars Bertram, Alexander J. Stratigos, George M. Spyrou
A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools. Database J. Biol. Databases Curation 2014 (2014)
Ioannis Andreadis, George M. Spyrou, Panos A. Ligomenides, Konstantina S. Nikita
Variations on breast density and subtlety of the findings require different computational intelligence pipelines for the diagnosis of clustered microcalcifications. BIBE (2013)
Efthymios Maneas, Stratis Tzoumas, Vasilis Ntziachristos, George M. Spyrou
Developing a simulator for multispectral optoacoustic tomography. BIBE (2013)
George M. Tzanoukos, Anastasios Gaitanis, Alexandros Georgakopoulos, Achilleas Chatziioannou, Sofia Chatziioannou, George M. Spyrou
Modeling of solitary pulmonary nodules in PET/CT images using Monte Carlo methods. BIBE (2013)
Emmanouil K. Ikonomakis, George M. Spyrou, Panos A. Ligomenides, Michael N. Vrahatis
Performance evaluation of clustering algorithms on microcalcifications as mammography findings. BIBE (2013)
Maria D. Paraskevopoulou, Ioannis S. Vlachos, Emmanouil Athanasiadis, George M. Spyrou
BiDaS: a web-based Monte Carlo BioData Simulator based on sequence/feature characteristics. Nucleic Acids Res. 41 (Webserver-Issue) (2013)
Ioannis Andreadis, George M. Spyrou, Panos A. Ligomenides, Konstantina S. Nikita
Generation of clustered microcalcifications' atlases for benign and malignant cases. BIBE (2013)
Katerina N. Karayianni, George M. Spyrou, Konstantina S. Nikita
Clustering microarray data using fuzzy clustering with viewpoints. BIBE (2012)
Argiris Sakellariou, Despina Sanoudou, George M. Spyrou
Combining multiple hypothesis testing and affinity propagation clustering leads to accurate, robust and sample size independent classification on gene expression data. BMC Bioinform. 13 (2012)
Alexandros C. Dimopoulos, John Lakoumentas, Argyro Antaraki, Antonis Frigas, Emmanouil K. Ikonomakis, Marinos Sampson, Anastasios Tagaris, Aikaterini Liakou, Emmanouil Athanasiadis, George M. Spyrou, Panos A. Ligomenides
e-Prolipsis: A web based risk estimation platform to support and register breast cancer diagnosis in Greece. BIBE (2012)
Emmanouil Athanasiadis, Zoe Cournia, George M. Spyrou
ChemBioServer: a web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery. Bioinform. 28 (22) (2012)
Paraskevi Gkeka, Emmanouil Athanasiadis, George M. Spyrou, Zoe Cournia
Enhancing the effectiveness of virtual screening by using the ChemBioServer: Application to the discovery of PI3Kα inhibitors. BIBE (2012)
Anastasia Alexandridou, Nikolas Dovrolis, George T. Tsangaris, Konstantina S. Nikita, George M. Spyrou
PepServe: a web server for peptide analysis, clustering and visualization. Nucleic Acids Res. 39 (Web-Server-Issue) (2011)
Argiris Sakellariou, Despina Sanoudou, George M. Spyrou
Investigating the Minimum Required Number of Genes for the Classification of Neuromuscular Disease Microarray Data. IEEE Trans. Inf. Technol. Biomed. 15 (3) (2011)
Georgia Giannakopoulou, George M. Spyrou, Argyro Antaraki, Ioannis Andreadis, Dimitra Koulocheri, Flora Zagouri, Afroditi Nonni, George M. Filippakis, Konstantina S. Nikita, Panos A. Ligomenides, George C. Zografos
Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer. Comput. Biol. Medicine 40 (11-12) (2010)
Ioannis K. Valavanis, George M. Spyrou, Konstantina S. Nikita
A similarity network approach for the analysis and comparison of protein sequence/structure sets. J. Biomed. Informatics 43 (2) (2010)
Anastasios Gaitanis, George Kontaxakis, George M. Spyrou, George Panayiotakis, George Tzanakos
Studying the properties of the updating coefficients in the OSEM algorithm for iterative image reconstruction in PET. Comput. Methods Programs Biomed. 99 (3) (2010)
Anastasios Gaitanis, George Kontaxakis, George M. Spyrou, George Panayiotakis, George Tzanakos
PET image reconstruction: A stopping rule for the MLEM algorithm based on properties of the updating coefficients. Comput. Medical Imaging Graph. 34 (2) (2010)
Antonis Frigas, George M. Spyrou, Argyro Antaraki, Elisabeth Patiraki, Konstantinos Koufopoulos, John Mantas, Panos A. Ligomenides
Design of a 'Smart' Patient Record System for Mammography Patients. MIE (2009)
Anastasia Alexandridou, George T. Tsangaris, Konstantinos N. Vougas, Konstantina S. Nikita, George M. Spyrou
UniMaP: finding unique mass and peptide signatures in the human proteome. Bioinform. 25 (22) (2009)
Anastasia Alexandridou, George T. Tsangaris, Konstantinos N. Vougas, Konstantina S. Nikita, George M. Spyrou
Peptide Finder: mapping measured molecular masses to peptides and proteins. Bioinform. 24 (19) (2008)
Vassilis Atlamazoglou, Trias Thireou, Anastasia Alexandridou, George M. Spyrou
A high throughput approach to keep alive a web-based database system for multiple search among published bioinformatics tools and databases. BIBE (2008)
Ioannis K. Valavanis, George M. Spyrou, Konstantina S. Nikita
Protein similarity networks and Genetic Algorithm driven feature selection for fold recognition. BIBE (2008)
Trias Thireou, George M. Spyrou, Vassilis Atlamazoglou
A Survey of the Availability of Primary Bioinformatics Web Resources. Genom. Proteom. Bioinform. 5 (1) (2007)
George M. Spyrou, Smaragda Kapsimalakou, Antonis Frigas, Konstantinos Koufopoulos, Stamatios Vassilaros, Panos A. Ligomenides
"Hippocrates-mst": a prototype for computer-aided microcalcification analysis and risk assessment for breast cancer. Medical Biol. Eng. Comput. 44 (11) (2006)
Antonis Frigas, Smaragda Kapsimalakou, George M. Spyrou, Konstantinos Koufopoulos, Stamatios Vassilaros, Aikaterini Chatzimichael, John Mantas, Panos A. Ligomenides
Evaluation of a Breast Cancer Computer Aided Diagnosis System. MIE (2006)
Xenofon E. Floros, George M. Spyrou, Konstantinos N. Vougas, George T. Tsangaris, Konstantina S. Nikita
Study on Preprocessing and Classifying Mass Spectral Raw Data Concerning Human Normal and Disease Cases. ISBMDA (2006)