Darren R. Flower

Publication Activity (10 Years)

Years Active: 1997-2023
Publications (10 Years): 6

Top Topics

Protein Functional

Tertiary Structure

Top Venues

Publications

Subhagata Chattopadhyay, Nhat Phuong Do, Darren R. Flower, Amit K. Chattopadhyay
Extracting prime protein targets as possible drug candidates: machine learning evaluation. Medical Biol. Eng. Comput. 61 (11) (2023)
Monica J. Quinzo, Esther M. Lafuente, Pilar Zuluaga, Darren R. Flower, Pedro A. Reche
Correction to: Computational assembly of a human Cytomegalovirus vaccine upon experimental epitope legacy. BMC Bioinform. 21 (1) (2020)
Monica J. Quinzo, Esther M. Lafuente, Pilar Zuluaga, Darren R. Flower, Pedro A. Reche
Computational assembly of a human Cytomegalovirus vaccine upon experimental epitope legacy. BMC Bioinform. (6) (2019)
Monica J. Quinzo, Esther M. Lafuente, Pedro A. Reche, Darren R. Flower
Computational design of a legacy-based epitope vaccine against Human Cytomegalovirus. BIBM (2018)
Enrique Audain, Yassel Ramos, Henning Hermjakob, Darren R. Flower, Yasset Pérez-Riverol
Accurate estimation of isoelectric point of protein and peptide based on amino acid sequences. Bioinform. 32 (6) (2016)
Qamar M. Sheikh, Derek Gatherer, Pedro A. Reche, Darren R. Flower
Towards the knowledge-based design of universal influenza epitope ensemble vaccines. Bioinform. 32 (21) (2016)
Amit K. Chattopadhyay, Diar Nasiev, Darren R. Flower
A statistical physics perspective on alignment-independent protein sequence comparison. Bioinform. 31 (15) (2015)
Egle Bunkute, Christopher Cummins, Fraser J. Crofts, Gareth Bunce, Ian T. Nabney, Darren R. Flower
PIP-DB: the Protein Isoelectric Point database. Bioinform. 31 (2) (2015)
Shahzad Mumtaz, Darren R. Flower, Ian T. Nabney
Multi-level Visualisation using Gaussian Process Latent Variable Models. IVAPP (2014)
Ivan Dimitrov, Darren R. Flower, Irini A. Doytchinova
AllerTOP - a server for in silico prediction of allergens. BMC Bioinform. 14 (S-6) (2013)
Shahzad Mumtaz, Ian T. Nabney, Darren R. Flower
Novel visualization methods for protein data. CIBCB (2012)
Ivan Dimitrov, Panayot Garnev, Darren R. Flower, Irini A. Doytchinova
EpiTOP - a proteochemometric tool for MHC class II binding prediction. Bioinform. 26 (16) (2010)
Hifzur Rahman Ansari, Darren R. Flower, G. P. S. Raghava
AntigenDB: an immunoinformatics database of pathogen antigens. Nucleic Acids Res. 38 (Database-Issue) (2010)
Andrew Secker, Matthew N. Davies, Alex Alves Freitas, Edward Clark, Jonathan Timmis, Darren R. Flower
Hierarchical classification of G-Protein-Coupled Receptors with data-driven selection of attributes and classifiers. Int. J. Data Min. Bioinform. 4 (2) (2010)
Andrew Secker, Matthew N. Davies, Alex Alves Freitas, Jonathan Timmis, Edward Clark, Darren R. Flower
An Artificial Immune System for Clustering Amino Acids in the Context of Protein Function Classification. J. Math. Model. Algorithms 8 (2) (2009)
Matthew N. Davies, Andrew Secker, Alex Alves Freitas, Edward Clark, Jonathan Timmis, Darren R. Flower
Optimizing amino acid groupings for GPCR classification. Bioinform. 24 (18) (2008)
Andrew Secker, Matthew N. Davies, Alex Alves Freitas, Jonathan Timmis, Edward Clark, Darren R. Flower
An Artificial Immune System for Evolving Amino Acid Clusters Tailored to Protein Function Prediction. ICARIS (2008)
Irini A. Doytchinova, Darren R. Flower
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines. BMC Bioinform. 8 (2007)
Irini A. Doytchinova, Darren R. Flower
Predicting Class I Major Histocompatibility Complex (MHC) Binders Using Multivariate Statistics: Comparison of Discriminant Analysis and Multiple Linear Regression. J. Chem. Inf. Model. 47 (1) (2007)
Matthew N. Davies, Andrew Secker, Alex Alves Freitas, Miguel Mendao, Jonathan Timmis, Darren R. Flower
On the hierarchical classification of G protein-coupled receptors. Bioinform. 23 (23) (2007)
Jesper Salomon, Darren R. Flower
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores. BMC Bioinform. 7 (2006)
Channa K. Hattotuwagama, Christopher P. Toseland, Pingping Guan, Debra J. Taylor, Shelley L. Hemsley, Irini A. Doytchinova, Darren R. Flower
Toward Prediction of Class II Mouse Major Histocompatibility Complex Peptide Binding Affinity: in Silico Bioinformatic Evaluation Using Partial Least Squares, a Robust Multivariate Statistical Technique. J. Chem. Inf. Model. 46 (3) (2006)
Irini A. Doytchinova, Pingping Guan, Darren R. Flower
EpiJen: a server for multistep T cell epitope prediction. BMC Bioinform. 7 (2006)
Wen Liu, Xiangshan Meng, Qiqi Xu, Darren R. Flower, Tongbin Li
Quantitative prediction of mouse class I MHC peptide binding affinity using support vector machine regression (SVR) models. BMC Bioinform. 7 (2006)
Christopher P. Toseland, Helen M. McSparron, Matthew N. Davies, Darren R. Flower
values. Nucleic Acids Res. 34 (Database-Issue) (2006)
Ji Wan, Wen Liu, Qiqi Xu, Yongliang Ren, Darren R. Flower, Tongbin Li
SVRMHC prediction server for MHC-binding peptides. BMC Bioinform. 7 (2006)
Irini A. Doytchinova, Valerie Walshe, Persephone Borrow, Darren R. Flower
Towards the chemometric dissection of peptide - HLA-A*0201 binding affinity: comparison of local and global QSAR models. J. Comput. Aided Mol. Des. 19 (3) (2005)
Channa K. Hattotuwagama, Irini A. Doytchinova, Darren R. Flower
In Silico Prediction of Peptide Binding Affinity to Class I Mouse Major Histocompatibility Complexes: A Comparative Molecular Similarity Index Analysis (CoMSIA) Study. J. Chem. Inf. Model. 45 (5) (2005)
Christopher P. Toseland, Helen M. McSparron, Darren R. Flower
DSD - An integrated, web-accessible database of Dehydrogenase Enzyme Stereospecificities. BMC Bioinform. 6 (2005)
Shunzhou Wan, Peter V. Coveney, Darren R. Flower
Large-scale molecular dynamics simulations of HLA-A*0201 complexed with a tumor-specific antigenic peptide: Can the α3 and β2m domains be neglected? J. Comput. Chem. 25 (15) (2004)
Pingping Guan, Irini A. Doytchinova, Christianna Zygouri, Darren R. Flower
MHCPred: a server for quantitative prediction of peptide-MHC binding. Nucleic Acids Res. 31 (13) (2003)
Helen M. McSparron, Martin J. Blythe, Christianna Zygouri, Irini A. Doytchinova, Darren R. Flower
JenPep: A Novel Computational Information Resource for Immunobiology and Vaccinology. J. Chem. Inf. Comput. Sci. 43 (4) (2003)
Terri K. Attwood, Paul Bradley, Darren R. Flower, Anna Gaulton, Neil Maudling, Alex L. Mitchell, G. Moulton, A. Nordle, K. Paine, P. Taylor, A. Uddin, Christianna Zygouri
PRINTS and its automatic supplement, prePRINTS. Nucleic Acids Res. 31 (1) (2003)
Paul D. Taylor, Terri K. Attwood, Darren R. Flower
BPROMPT: a consensus server for membrane protein prediction. Nucleic Acids Res. 31 (13) (2003)
Irini A. Doytchinova, Darren R. Flower
Towards the in silico identification of class II restricted T-cell epitopes: a partial least squares iterative self-consistent algorithm for affinity prediction. Bioinform. 19 (17) (2003)
Christian Schönbach, Judice L. Y. Koh, Darren R. Flower, Limsoon Wong, Vladimir Brusic
FIMM, a database of functional molecular immunology: update 2002. Nucleic Acids Res. 30 (1) (2002)
Terri K. Attwood, Martin J. Blythe, Darren R. Flower, Anna Gaulton, J. E. Mabey, Neil Maudling, L. McGregor, Alex L. Mitchell, G. Moulton, K. Paine, Philip Scordis
PRINTS and PRINTS-S shed light on protein ancestry. Nucleic Acids Res. 30 (1) (2002)
Martin J. Blythe, Irini A. Doytchinova, Darren R. Flower
JenPep: a database of quantitative functional peptide data for immunology. Bioinform. 18 (3) (2002)
Irini A. Doytchinova, Darren R. Flower
A Comparative Molecular Similarity Index Analysis (CoMSIA) study identifies an HLA-A2 binding supermotif. J. Comput. Aided Mol. Des. 16 (8-9) (2002)
Terri K. Attwood, Michael D. R. Croning, Darren R. Flower, A. P. Lewis, J. E. Mabey, Philip Scordis, J. N. Selley, W. Wright
PRINTS-S: the database formerly known as PRINTS. Nucleic Acids Res. 28 (1) (2000)
Philip Scordis, Darren R. Flower, Terri K. Attwood
FingerPRINTScan: intelligent searching of the PRINTS motif database. Bioinform. 15 (10) (1999)
Terri K. Attwood, Darren R. Flower, A. P. Lewis, J. E. Mabey, S. R. Morgan, Philip Scordis, J. N. Selley, W. Wright
PRINTS prepares for the new millennium. Nucleic Acids Res. 27 (1) (1999)
Terri K. Attwood, Michael E. Beck, Darren R. Flower, Philip Scordis, J. N. Selley
The PRINTS protein fingerprint database in its fifth year. Nucleic Acids Res. 26 (1) (1998)
Darren R. Flower
On the Properties of Bit String-Based Measures of Chemical Similarity. J. Chem. Inf. Comput. Sci. 38 (3) (1998)
Terri K. Attwood, H. Avison, Michael E. Beck, Maria C. Bewley, Alan J. Bleasby, F. Brewster, P. Cooper, Kirill Degtyarenko, A. J. Geddes, Darren R. Flower, M. P. Kelly, Shaun Lott, K. M. Measures, David J. Parry-Smith, D. N. Perkins, Philip Scordis, David Scott, C. Worledge
The PRINTS Database of Protein Fingerprints: A Novel Information Resource for Computational Molecular Biology. J. Chem. Inf. Comput. Sci. 37 (3) (1997)