Statistical method evaluation for differentially methylated CpGs in base resolution next-generation DNA sequencing data.
Yun ZhangSaurabh BahetiZhifu SunPublished in: Briefings Bioinform. (2018)
Keyphrases
- synthetic data
- statistical methods
- data sets
- database
- correlation analysis
- test data
- prior knowledge
- input data
- noisy data
- evaluation method
- data analysis
- statistical significance
- statistical model
- statistical information
- data processing
- data collection
- clustering method
- pairwise
- image data
- preprocessing
- data structure
- missing data
- training data
- spectral clustering
- prior information
- high quality
- training samples
- low resolution
- statistical analysis
- contingency tables
- kernel canonical correlation analysis
- evaluation model
- data points
- objective function
- databases
- real time