Confidence intervals by constrained optimization - An algorithm and software package for practical identifiability analysis in systems biology.
Ivan I. BorisovEugeny A. MetelkinPublished in: PLoS Comput. Biol. (2020)
Keyphrases
- constrained optimization
- software package
- objective function
- systems biology
- learning algorithm
- optimal solution
- k means
- confidence intervals
- computational complexity
- search space
- dynamic programming
- upper bound
- np hard
- penalty function
- monte carlo
- statistical analysis
- real world
- data points
- open source
- probabilistic model
- neural network
- reinforcement learning
- training data
- information retrieval
- machine learning