Examination of the relationship between essential genes in PPI network and hub proteins in reverse nearest neighbor topology.
Kang NingHoong Kee NgSriganesh SrihariHon Wai LeongAlexey I. NesvizhskiiPublished in: BMC Bioinform. (2010)
Keyphrases
- protein protein interactions
- ppi networks
- protein complexes
- protein protein interaction networks
- functional modules
- protein interaction
- reverse nearest neighbor
- essential genes
- protein sequences
- gene ontology
- nearest neighbor
- protein interaction networks
- computational methods
- saccharomyces cerevisiae
- computational approaches
- network structure
- protein function
- neural network
- biological data
- query processing
- multi type
- interaction networks
- complex networks
- microarray data
- amino acids
- biomedical literature
- data sets
- biological networks
- computational biology