Assessing concordance among human, in silico predictions and functional assays on genetic variant classification.
Jiaqi LuoTianliangwen ZhouXiaobin YouYi ZiXiaoting LiYangming WuZhaoji LanQihuan ZhiDandan YiLei XuAng LiZaixuan ZhongMei ZhuGang SunTao ZhuJianmei RaoLuhua LinJianfeng SangYujian ShiPublished in: Bioinform. (2019)
Keyphrases
- classification accuracy
- classification systems
- pattern classification
- machine learning
- automatic classification
- classification algorithm
- model selection
- support vector machine svm
- class labels
- support vector
- classification method
- biological data
- training samples
- classification models
- feature selection
- human subjects
- data sets
- active learning
- classification scheme
- genetic algorithm
- predictive accuracy
- classification rules
- decision rules
- feature space
- supervised learning
- support vector machine