Phenotypic categorization of genetic skin diseases reveals new relations between phenotypes, genes and pathways.
Ruslan SadreyevJamison D. FeramiscoHensin TsaoNick V. GrishinPublished in: Bioinform. (2009)
Keyphrases
- single nucleotide polymorphisms
- complex diseases
- high throughput
- genome wide
- human genome
- genome wide association studies
- gene gene interactions
- dna sequences
- computational approaches
- biological processes
- copy number
- association studies
- biological data
- differential expression
- statistical tests
- genotype phenotype
- statistical methods
- biological pathways
- highly correlated
- microarray data
- gene sets
- gene expression
- expression profiles
- microarray
- gene gene
- text categorization
- feature selection
- metabolic pathways
- genetic variation
- systems biology
- gene expression data
- signaling pathways
- protein interaction data
- genomic data
- computational methods