Discovering mutated driver genes through a robust and sparse co-regularized matrix factorization framework with prior information from mRNA expression patterns and interaction network.
Jianing XiMinghui WangAo LiPublished in: BMC Bioinform. (2018)
Keyphrases
- prior information
- matrix factorization
- microarray data
- gene expression
- expression patterns
- prior knowledge
- high throughput
- genome wide
- collaborative filtering
- regulatory networks
- recommender systems
- bayesian inference
- data sets
- low rank
- experimental conditions
- gene expression analysis
- gene expression patterns
- feature selection
- learning algorithm
- high dimensional
- gene expression data
- gene ontology
- gene expression profiles
- microarray
- unsupervised learning