Disease association tests by inferring ancestral haplotypes using a hidden markov model.
Shu-Yi SuDavid J. BaldingLachlan J. M. CoinPublished in: Bioinform. (2008)
Keyphrases
- hidden markov models
- genetic variation
- complex diseases
- single nucleotide polymorphisms
- speech recognition
- sequence data
- high throughput
- markov models
- genome wide association studies
- copy number
- missing data
- gesture recognition
- sequential data
- genome wide
- markov model
- human genome
- viterbi algorithm
- dynamic probabilistic networks
- conditional random fields
- kernel density
- hidden states
- biological data
- microarray
- association studies
- mixture distributions
- continuous hidden markov models