Modelling Negative Feedback Networks for Activating Transcription Factor 3 Predicts a Dominant Role for miRNAs in Immediate Early Gene Regulation.
Marcus J. TindallAngela ClerkPublished in: PLoS Comput. Biol. (2014)
Keyphrases
- gene regulation
- transcription factors
- gene regulatory networks
- gene expression
- binding sites
- microarray
- gene expression data
- systems biology
- genome wide
- biological networks
- network model
- biological systems
- regulatory networks
- component analysis
- dna sequences
- computational biology
- biological processes
- genomic sequences
- saccharomyces cerevisiae
- dna binding
- microarray data
- high throughput
- co occurrence
- reverse engineering
- transcription factor binding sites
- biomedical literature
- complex networks
- statistical tests
- community structure
- complex systems
- statistical analysis
- relevance feedback
- dynamic bayesian networks
- high dimensionality
- machine learning