A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens.
Mehdi BouhaddouAnne Marie BarretteAlan D. SternRick J. KochMatthew S. DiStefanoEric A. RieselLuis C. SantosAnnie L. TanAlex E. MertzMarc R. BirtwistlePublished in: PLoS Comput. Biol. (2018)
Keyphrases
- experimental data
- prior knowledge
- data sets
- input data
- database
- learning models
- test data
- probability distribution
- data processing
- simulation data
- data collection
- data structure
- computational model
- empirical data
- measured data
- high dimensional data
- mathematical model
- raw data
- training data
- probabilistic model
- statistical analysis
- data analysis
- statistical methods
- similarity measure