Discovering Motifs With Transcription Factor Domain Knowledge.
Henry C. M. LeungFrancis Y. L. ChinBethany Man-Yee ChanPublished in: Pacific Symposium on Biocomputing (2007)
Keyphrases
- transcription factors
- domain knowledge
- binding sites
- gene expression
- dna sequences
- component analysis
- microarray
- genome wide
- dna binding
- motif discovery
- computational biology
- regulatory networks
- gene regulation
- transcription factor binding sites
- systems biology
- sequence data
- high throughput
- co occurrence
- highly correlated
- saccharomyces cerevisiae
- biomedical literature
- cis regulatory
- statistical significance
- domain ontology
- machine learning
- microarray data
- high dimensionality
- semantic information