ShrinkCRISPR: a flexible method for differential fitness analysis of CRISPR-Cas9 screen data.
Renaud L. M. TissierJanne J. M. van SchieRob M. F. WolthuisJob de LangeRenée X. de MenezesPublished in: BMC Bioinform. (2023)
Keyphrases
- synthetic data
- data analysis
- missing data
- correlation analysis
- statistical analysis
- data sets
- input data
- test data
- raw data
- database
- data structure
- preprocessing
- information loss
- high dimensional data
- detection method
- data distribution
- statistical methods
- original data
- high accuracy
- data sources
- computational cost
- cost function
- prior knowledge
- noisy data
- contingency tables
- clustering method
- data processing
- genetic programming
- image data
- significant improvement
- computational complexity
- neural network
- particle swarm optimization
- data acquisition
- data mining techniques
- statistical significance
- multivariate time series