Molecular modelling studies of synthesized pentacyclo-undecane peptides as potential HIV-1 wild type C-SA protease inhibitors.
Bahareh HonarparvarHendrik G. KrugerMahmoud E. S. SolimanGlenn E. M. MaguireThavendran GovenderPublished in: J. Cheminformatics (2013)
Keyphrases
- hiv protease
- human immunodeficiency virus
- drug resistance
- coarse grained
- fine grained
- protein protein interactions
- sequence analysis
- linear support vector machines
- simulated annealing
- high precision
- encoding schemes
- three dimensional
- early stage
- pattern classification
- drug discovery
- protein structure prediction
- high level