MUCHA: multiple chemical alignment algorithm to identify building block substructures of orphan secondary metabolites.
Masaaki KoteraToshiaki TokimatsuMinoru KanehisaSusumu GotoPublished in: BMC Bioinform. (2011)
Keyphrases
- building blocks
- learning algorithm
- theoretical analysis
- computationally efficient
- optimization algorithm
- significant improvement
- times faster
- cost function
- high accuracy
- improved algorithm
- detection algorithm
- expectation maximization
- simulated annealing
- computational cost
- dynamic programming
- k means
- databases
- probabilistic model
- input data
- experimental evaluation
- search space
- segmentation algorithm
- computational complexity
- objective function
- recognition algorithm
- data sets