Unsupervised Clustering of Subcellular Protein Expression Patterns in High-Throughput Microscopy Images Reveals Protein Complexes and Functional Relationships between Proteins.
Louis-François HandfieldYolanda T. ChongJibril SimmonsBrenda J. AndrewsAlan M. MosesPublished in: PLoS Comput. Biol. (2013)
Keyphrases
- high throughput
- protein protein interactions
- protein complexes
- protein function
- protein interaction
- biological processes
- biological data
- biological knowledge
- microarray
- protein interaction data
- genome wide
- genomic data
- systems biology
- protein interaction networks
- protein protein interaction networks
- gene ontology
- functional modules
- biomedical literature
- ppi networks
- cell cycle
- gene expression
- gene expression data
- mass spectrometry
- computational approaches
- interaction networks
- molecular biology
- biological networks
- data acquisition
- expression profiles
- regulatory networks
- experimental conditions
- computational biology
- signaling pathways
- computational tools
- image segmentation
- microarray data