A model-based scan statistic for identifying extreme chromosomal regions of gene expression in human tumors.
Albert M. LevinDebashis GhoshKathleen R. ChoSharon L. R. KardiaPublished in: Bioinform. (2005)
Keyphrases
- gene expression
- scan statistic
- microarray
- gene expression data
- event detection
- space time
- expression profiles
- microarray data
- gene expression profiles
- biological processes
- protein interaction
- regulatory networks
- binding sites
- dna microarray
- gene expression patterns
- gene regulation
- biological networks
- microarray datasets
- copy number
- data sets
- transcription factors
- machine learning
- high dimensionality
- rectangular regions
- disease outbreaks
- feature extraction
- data structure
- feature space
- spatio temporal
- input image
- particle filter