ANTENNA, a Multi-Rank, Multi-Layered Recommender System for Inferring Reliable Drug-Gene-Disease Associations: Repurposing Diazoxide as a Targeted Anti-Cancer Therapy.
Annie WangHansaim LimShu-Yuan ChengLei XiePublished in: IEEE ACM Trans. Comput. Biol. Bioinform. (2018)
Keyphrases
- multi layered
- disease progression
- recommender systems
- candidate genes
- genetic variation
- dna microarray
- clinical trials
- gene selection
- gene expression profiles
- biological entities
- gene gene
- disease genes
- gene expression
- microarray
- cancer treatment
- neural learning
- related genes
- relevant genes
- microarray data
- protein protein interaction networks
- early diagnosis
- cancer patients
- gene sets
- cross sectional
- breast cancer
- sequence data
- high throughput
- biological knowledge
- collaborative filtering
- gene networks
- ovarian cancer
- differential expression
- cancer diagnosis
- gene clusters
- gene expression data
- prostate cancer
- genome wide
- association rules
- drug discovery
- outcome prediction
- user profiles
- gene ontology terms
- gene expression data sets
- copy number
- user preferences
- human genome
- genome wide association studies
- medical doctors
- biological networks
- statistical significance