Anatomically-distinct genetic associations of APOE ɛ4 allele load with regional cortical atrophy in Alzheimer's disease.
Nicola FilippiniAnil RaoSally WettenRachel A. GibsonMichael BorrieDanilo GuzmanAndrew KerteszInge Loy-EnglishJulie WilliamsThomas E. NicholsBrandon J. WhitcherPaul M. MatthewsPublished in: NeuroImage (2009)
Keyphrases
- genome wide association studies
- genetic variation
- gene gene
- complex diseases
- microarray
- genome wide
- sequence data
- gene networks
- high throughput
- gray matter
- gene gene interactions
- load balancing
- human genome
- white matter
- association rules
- biological knowledge
- genetic algorithm
- early diagnosis
- copy number
- healthy subjects
- receptive fields
- computer aided diagnosis
- single nucleotide polymorphisms
- brain anatomy
- blood pressure
- visual cortex
- disease diagnosis
- cerebral cortex
- cortical surface
- mr images
- biological data
- outbreak detection