eProbalign: generation and manipulation of multiple sequence alignments using partition function posterior probabilities.
Satish ChikkagoudarUsman RoshanDennis R. LivesayPublished in: Nucleic Acids Res. (2007)
Keyphrases
- posterior probability
- partition function
- probability density function
- bayesian framework
- multiple sequence alignments
- bayesian networks
- approximate inference
- generative model
- probability distribution
- markov random field
- random fields
- prior knowledge
- belief propagation
- upper and lower bounds
- em algorithm
- structure learning
- density estimation
- protein sequences
- pairwise
- statistical methods
- expectation maximization
- density function
- graphical models
- conditional random fields
- parameter estimation
- conditional probabilities
- probabilistic model
- statistical model
- maximum likelihood estimation
- markov networks
- message passing
- markov chain monte carlo