Sequence Motifs in MADS Transcription Factors Responsible for Specificity and Diversification of Protein-Protein Interaction.
Aalt D. J. van DijkGiuseppa MorabitoMartijn FiersRoeland C. H. J. van HamGerco C. AngenentRichard G. H. ImminkPublished in: PLoS Comput. Biol. (2010)
Keyphrases
- transcription factors
- protein protein interactions
- biomedical literature
- transcription factor binding sites
- saccharomyces cerevisiae
- systems biology
- binding sites
- regulatory networks
- biological processes
- protein interaction
- microarray
- high throughput
- cell cycle
- genomic data
- genome wide
- dna sequences
- biological sequences
- dna binding
- gene expression
- component analysis
- gene ontology
- signaling pathways
- biological data
- computational biology
- motif discovery
- gene regulation
- protein complexes
- computational methods
- functional modules
- biological networks
- high precision
- protein function
- protein families
- co occurrence
- sequence data
- network topology
- high dimensionality
- biological systems
- computational approaches
- highly correlated
- structural properties
- statistical significance
- genomic sequences
- protein protein interaction networks
- microarray data
- gene expression data
- cis regulatory
- molecular biology
- high dimensional