DriverRWH: discovering cancer driver genes by random walk on a gene mutation hypergraph.
Chenye WangJunhan ShiJiansheng CaiYusen ZhangXiaoqi ZhengNaiqian ZhangPublished in: BMC Bioinform. (2022)
Keyphrases
- random walk
- gene selection
- dna microarray
- candidate genes
- gene expression profiles
- gene expression
- microarray
- relevant genes
- cancer classification
- gene expression data
- microarray data
- gene ontology terms
- cancer diagnosis
- hyper graph
- gene expression datasets
- gene expression data sets
- colon cancer
- microarray technology
- related genes
- gene sets
- biologically significant
- microarray datasets
- gene ontology
- gene clusters
- higher order
- gene expression patterns
- directed graph
- markov chain
- differential expression
- gene function
- gene networks
- cancer datasets
- link prediction
- gene expression analysis
- feature selection
- gene regulatory networks
- high throughput
- markov random walk
- pairwise
- biologically meaningful
- biological processes
- transition probabilities
- transition probability matrix
- breast cancer
- regulatory networks
- escherichia coli
- cell lines