A flexible volumetric comparison of protein cavities can reveal patterns in ligand binding specificity.
Ziyi GuoTrevor KuhlengelSteven R. StinsonSeth BlumenthalBrian Yuan ChenSoutir BandyopadhyayPublished in: BCB (2014)
Keyphrases
- transcription factor binding sites
- drug design
- drug discovery
- chemical compounds
- data mining techniques
- protein sequences
- binding sites
- protein protein interactions
- virtual screening
- dna binding
- pattern discovery
- protein structure prediction
- amino acids
- protein protein
- three dimensional
- sequence alignment
- protein function
- dna sequences
- high throughput