A new method for ligand docking to flexible receptors by dual alanine scanning and refinement (SCARE).
Giovanni BottegoniIrina KufarevaMaxim TotrovRuben AbagyanPublished in: J. Comput. Aided Mol. Des. (2008)
Keyphrases
- high accuracy
- high precision
- cost function
- computational cost
- detection method
- classification method
- theoretical analysis
- main contribution
- fully automatic
- similarity measure
- experimental evaluation
- probabilistic model
- image processing
- synthetic data
- medical images
- segmentation method
- evaluation method
- clustering method
- input data
- data sets
- edge detection
- computational complexity
- objective function
- machine learning