A cross-species analysis method to analyze animal models' similarity to human's disease state.
Shu-Hao YuLulu ZhengYun LiChunyan LiChenchen MaYixue LiXuan LiPei HaoPublished in: BMC Syst. Biol. (2012)
Keyphrases
- machine learning methods
- computational cost
- probabilistic model
- similarity measure
- computational complexity
- significant improvement
- state space
- statistical model
- modeling method
- preprocessing
- dynamic programming
- high accuracy
- high precision
- distance function
- clustering method
- statistical analysis
- cost function
- objective function
- distance metric
- em algorithm