Identification of hot-spot residues in protein-protein interactions by computational docking.
Solène GrosdidierJuan Fernández-RecioPublished in: BMC Bioinform. (2008)
Keyphrases
- protein protein interactions
- hot spots
- protein protein
- protein function
- computational methods
- high throughput
- network topology
- predicting protein protein interactions
- biological data
- biological processes
- protein interaction
- high precision
- biomedical literature
- functional modules
- gene ontology
- network analysis
- predicting protein
- structural properties
- protein complexes
- biological networks
- experimentally determined
- multiple sequence alignments
- protein interaction data
- protein interaction networks
- systems biology
- computational approaches
- mass spectrometry
- amino acid sequences
- protein structure
- computational tools
- social networks
- response time