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Correcting for cancer genome size and tumour cell content enables better estimation of copy number alterations from next-generation sequence data.
Arief Gusnanto
Henry M. Wood
Yudi Pawitan
Pamela Rabbitts
Stefano Berri
Published in:
Bioinform. (2012)
Keyphrases
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copy number
sequence data
sequence analysis
noise level
dna copy number
nucleotide sequences
genome sequences
binding sites
profile hidden markov models