The detection of risk pathways, regulated by miRNAs, via the integration of sample-matched miRNA-mRNA profiles and pathway structure.
Jing LiChunquan LiJunwei HanChunlong ZhangDesi ShangQianlan YaoYunpeng ZhangYanjun XuWei LiuMeng ZhouHaixiu YangFei SuXia LiPublished in: J. Biomed. Informatics (2014)
Keyphrases
- regulatory networks
- genome wide
- signaling pathways
- gene function
- computational methods
- gene expression
- secondary structure
- microarray
- expression profiles
- post transcriptional
- gene regulatory networks
- gene ontology
- high throughput
- gene regulation
- transcription factors
- rna molecules
- computational biology
- gene expression data
- biological data
- biological processes
- systems biology
- binding sites
- biological systems
- protein protein interactions
- metabolic pathways
- gene networks
- network model
- microarray data
- data sets
- microarray data analysis
- molecular biology