Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants.
Stuart A. MacGowanMichael I. BartonMikhail KutuzovOmer DushekP. Anton van der MerweGeoffrey J. BartonPublished in: PLoS Comput. Biol. (2022)