Efficient Parameter Estimation for DNA Kinetics Modeled as Continuous-Time Markov Chains.
Sedigheh ZolaktafFrits DannenbergErik WinfreeAlexandre Bouchard-CôtéMark SchmidtAnne CondonPublished in: DNA (2019)
Keyphrases
- parameter estimation
- maximum likelihood
- markov random field
- model selection
- em algorithm
- least squares
- parameter estimation algorithm
- random fields
- expectation maximization
- model fitting
- experimental data
- approximate inference
- parameter estimates
- estimation problems
- structure learning
- continuous time markov chains
- particle filter
- higher order
- high dimensional