COACH-D: improved protein-ligand binding sites prediction with refined ligand-binding poses through molecular docking.
Qi WuZhenling PengYang ZhangJianyi YangPublished in: Nucleic Acids Res. (2018)
Keyphrases
- protein protein
- protein protein interactions
- hiv protease
- binding sites
- virtual screening
- dna binding
- drug design
- predicting protein
- protein interaction
- computational methods
- high throughput
- transcription factor binding sites
- dna sequences
- transcription factors
- protein function
- gene expression
- transcriptional regulation
- network topology
- interaction networks
- genome wide
- biomedical literature
- high precision
- biological processes
- motif discovery
- protein structure
- gene ontology
- protein sequences
- biological data
- protein complexes
- biological networks
- genomic data
- sequence alignment
- functional modules
- biological sequences
- statistical significance
- computational approaches
- protein structure prediction
- microarray
- sequence data
- network analysis
- regulatory elements
- molecular biology
- amino acid sequences
- saccharomyces cerevisiae
- regulatory networks