Pharmacophore Fingerprint-Based Approach to Binding Site Subpocket Similarity and Its Application to Bioisostere Replacement.
David J. WoodJacob de VliegMarkus WagenerTina RitschelPublished in: J. Chem. Inf. Model. (2012)
Keyphrases
- binding sites
- sequence data
- dna sequences
- gene expression
- statistical significance
- transcription factors
- similarity measure
- motif discovery
- biological sequences
- protein protein
- statistically significant
- semantic similarity
- protein interaction
- transcription factor binding sites
- regulatory elements
- virtual screening
- distance function