Boosting Prediction Performance of Protein-Protein Interaction Hot Spots by Using Structural Neighborhood Properties.
Lei DengJihong GuanXiaoming WeiYuan YiQiangfeng Cliff ZhangShuigeng ZhouPublished in: J. Comput. Biol. (2013)
Keyphrases
- hot spots
- protein protein interactions
- experimentally determined
- protein interaction
- predicting protein
- drug design
- wet lab
- structural properties
- computational methods
- high throughput
- protein function prediction
- biological processes
- protein function
- network topology
- genomic data
- predicting protein protein interactions
- functional modules
- biological data
- high precision
- protein complexes
- protein interaction networks
- computational approaches
- ppi networks
- gene ontology
- biological networks
- multiple sequence alignments
- network analysis
- protein interaction data
- gene expression