Connectivity Significance for Disease Gene Prioritization in an Expanding Universe.
Manuela PettiDaniele BizzarriAntonella VerrientiRosa FalconeLorenzo FarinaPublished in: IEEE ACM Trans. Comput. Biol. Bioinform. (2020)
Keyphrases
- disease genes
- candidate genes
- gene function
- gene sets
- gene expression
- statistical significance
- gene gene
- microarray
- differentially expressed genes
- dna microarray
- protein protein interaction networks
- related genes
- biological entities
- gene selection
- functional genomics
- complex diseases
- gene clusters
- gene networks
- gene expression data
- gene gene interactions
- molecular level
- connected components
- gene ontology
- genome wide
- escherichia coli
- outbreak detection
- disease diagnosis
- association studies
- genomic data
- gene expression profiles
- gene regulatory networks
- microarray data
- gene expression analysis
- linkage analysis
- single nucleotide polymorphisms
- linkage disequilibrium
- biomedical literature
- differential expression
- gene interactions