Set-base dynamical parameter estimation and model invalidation for biochemical reaction networks.
Philipp RumschinskiSteffen BorchersSandro BosioRobert WeismantelRolf FindeisenPublished in: BMC Syst. Biol. (2010)
Keyphrases
- parameter estimation
- model selection
- experimental data
- parameter estimation algorithm
- parameter values
- maximum likelihood
- em algorithm
- least squares
- statistical models
- random fields
- probability distribution
- model fitting
- probabilistic model
- network structure
- prior knowledge
- markov random field
- approximate inference
- maximum likelihood estimation
- estimation problems
- expectation maximization
- parameter estimates
- maximum likelihood estimates