: Advances in Protein-Ligand Docking with Explicitly Specified Binding Site Flexibility.
Pradeep Anand RavindranathStefano ForliDavid S. GoodsellArthur J. OlsonMichel F. SannerPublished in: PLoS Comput. Biol. (2015)
Keyphrases
- binding sites
- virtual screening
- dna binding
- protein protein
- ligand docking
- protein interaction
- regulatory elements
- sequence alignment
- dna sequences
- transcription factor binding sites
- similarity searching
- protein sequences
- sequence data
- drug discovery
- gene expression
- protein protein interactions
- transcription factors
- computational methods
- protein families
- protein structure
- high throughput
- motif discovery
- statistical significance
- scoring function
- biological sequences
- predicting protein
- regulatory networks
- similarity search
- cis regulatory
- gene expression levels
- amino acids
- drug design
- protein function
- protein complexes
- protein interaction networks
- computational biology
- interaction networks
- genome sequences
- amino acid sequences
- functional modules