Structure-based prediction of DNA-binding proteins by structural alignment and a volume-fraction corrected DFIRE-based energy function.
Huiying ZhaoYuedong YangYaoqi ZhouPublished in: Bioinform. (2010)
Keyphrases
- energy function
- dna binding
- sequence similarity
- graph cuts
- energy minimization
- markov random field
- wet lab
- protein interaction
- energy landscape
- contact map
- protein structure prediction
- image segmentation
- active contours
- hopfield neural network
- belief propagation
- binding sites
- biological processes
- computational methods
- genome wide
- level set
- structural properties
- transcription factors
- secondary structure
- amino acids