Predicting functional regulatory SNPs in the human antimicrobial peptide genes DEFB1 and CAMP in tuberculosis and HIV/AIDS.
Adolfo Flores Saiffe FaríasEnrique Jaime Herrera-LópezCristopher Jorge Moreno VázquezWentian LiErnesto Prado Montes de OcaPublished in: Comput. Biol. Chem. (2015)
Keyphrases
- single nucleotide polymorphisms
- hiv aids
- complex diseases
- gene function
- genome wide
- gene regulatory
- functional properties
- gene expression
- genetic regulatory networks
- computational approaches
- dna sequences
- microarray data
- high throughput
- genomic data
- regulatory elements
- evolutionary history
- human genome
- tandem mass spectra
- transcription factors
- amino acids
- statistical methods
- high dimensional
- protein families
- gene sets
- variable selection
- statistical tests
- learning environment