Functional Characterization of Transcription Factor Motifs Using Cross-species Comparison across Large Evolutionary Distances.
Jaebum KimRyan CunninghamBrian JamesStefan WyderJoshua D. GibsonOliver NiehuisEvgeny M. ZdobnovHugh M. RobertsonGene E. RobinsonJohn H. WerrenSaurabh SinhaPublished in: PLoS Comput. Biol. (2010)
Keyphrases
- transcription factors
- binding sites
- protein families
- dna sequences
- gene expression
- dna binding
- microarray
- phylogenetic trees
- computational biology
- motif discovery
- genome wide
- component analysis
- transcription factor binding sites
- genome sequences
- regulatory networks
- systems biology
- saccharomyces cerevisiae
- sequence data
- biomedical literature
- gene expression data
- co occurrence
- biological sequences
- biological processes
- gene regulation
- text mining
- genomic sequences
- non stationary
- high throughput
- protein sequences
- information extraction
- highly correlated