A framework for scalable parameter estimation of gene circuit models using structural information.
Hiroyuki KuwaharaMing FanSuojin WangXin GaoPublished in: Bioinform. (2013)
Keyphrases
- parameter estimation
- structural information
- statistical models
- model selection
- maximum likelihood
- random fields
- least squares
- expectation maximization
- em algorithm
- model fitting
- probabilistic model
- markov random field
- approximate inference
- parameter estimation algorithm
- bayesian framework
- posterior distribution
- bayesian model selection
- structural similarity
- artificial intelligence
- structure learning
- semantic information
- gene regulatory networks
- estimation problems
- machine learning
- stochastic logic programs