Hybrid metabolic flux analysis: combining stoichiometric and statistical constraints to model the formation of complex recombinant products.
Nuno CarinhasVicente BernalAna P. TeixeiraManuel J. T. CarrondoPaula M. AlvesRui OliveiraPublished in: BMC Syst. Biol. (2011)
Keyphrases
- statistical analysis
- probabilistic model
- high level
- statistical model
- computational model
- statistical models
- management system
- prior knowledge
- probability distribution
- complex systems
- sensitivity analysis
- geometric constraints
- cost function
- data sets
- mathematical model
- artificial neural networks
- video sequences
- constraint programming
- goodness of fit
- physical constraints