LOMA: A fast method to generate efficient tagged-random primers despite amplification bias of random PCR on pathogens.
Wah-Heng LeeChristopher W. WongWan Yee LeongLance D. MillerWing-Kin SungPublished in: BMC Bioinform. (2008)
Keyphrases
- high precision
- computational cost
- high accuracy
- highly efficient
- preprocessing
- significant improvement
- classification method
- experimental evaluation
- synthetic data
- detection method
- input data
- theoretical analysis
- generation method
- high efficiency
- segmentation method
- clustering method
- main contribution
- computationally efficient
- mutual information
- pairwise
- objective function
- detection algorithm
- feature set
- dynamic programming
- cost function
- optimization method
- dna sequences
- evaluation method
- similarity measure
- neural network