Discovery of a Novel DCAF1 Ligand Using a Drug-Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets.
Serah W. KimaniJulie OwenStuart R. GreenFengling LiYanjun LiAiping DongPeter J. BrownSuzanne AcklooDavid KuterCindy YangMiranda MacaskillStephen Scott MackinnonCheryl H. ArrowsmithMatthieu SchapiraVijay ShahaniLevon HalabelianPublished in: J. Chem. Inf. Model. (2023)
Keyphrases
- prediction model
- machine learning
- regression model
- drug design
- data mining
- wavelet neural network
- machine learning methods
- response surface methodology
- drug discovery
- neural network
- knowledge discovery
- virtual screening
- exponential smoothing
- predictive model
- ls svm
- stepwise regression
- fuzzy neural network
- bp neural network
- human computer interaction
- machine learning algorithms
- bp network
- discovery process
- software reliability
- customer churn
- text mining
- support vector machine
- learning algorithm
- learning tasks
- high throughput
- association rules