A Probabilistic Model of Local Sequence Alignment That Simplifies Statistical Significance Estimation.
Sean R. EddyPublished in: PLoS Comput. Biol. (2008)
Keyphrases
- statistical significance
- sequence alignment
- binding sites
- probabilistic model
- pairwise
- statistically significant
- psi blast
- transcription factors
- statistical tests
- bayesian networks
- language model
- multiple alignment
- differential expression
- protein sequences
- dynamic programming
- amino acids
- permutation tests
- protein structure
- dna sequences