Computation of biochemical pathway fluctuations beyond the linear noise approximation using iNA.
Philipp ThomasHannes MatuschekRamon GrimaPublished in: BIBM (2012)
Keyphrases
- efficient computation
- closed form
- exact computation
- linear approximation
- numerical integration
- signal to noise ratio
- increase in computational complexity
- noise sensitivity
- signal transduction pathways
- sequential monte carlo methods
- additive noise
- experimental data
- square root
- noisy data
- error tolerance
- linear model
- noise level
- image noise
- statistically independent
- linear functions
- missing data
- noise reduction
- gauss seidel
- noisy observations
- approximation algorithms
- sparse approximation
- linear complexity
- random noise
- approximation error