Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool.
Raymond K. AuerbachBin ChenAtul J. ButtePublished in: Bioinform. (2013)
Keyphrases
- transcription factors
- gene expression
- chip seq
- dna binding
- binding sites
- microarray
- gene regulation
- regulatory networks
- biological processes
- saccharomyces cerevisiae
- systems biology
- component analysis
- genome wide
- gene expression data
- biclustering algorithms
- transcription factor binding sites
- dna sequences
- biomedical literature
- co occurrence
- microarray data
- computational biology
- gene sets
- high throughput
- statistical significance
- regulatory elements
- highly correlated
- signaling pathways
- gene selection
- gene ontology
- biological networks
- gene expression patterns
- human genome
- microarray datasets
- protein interaction
- experimental conditions
- molecular biology
- sequence data
- data sets