Estimation of parameters in rational reaction rates of molecular biological systems via weighted least squares.
Fang-Xiang WuLei MuZhong-Ke ShiPublished in: Int. J. Syst. Sci. (2010)
Keyphrases
- motion model
- biological systems
- weighted least squares
- motion parameters
- least squares
- signal transduction
- parameter estimation
- biologically inspired
- complex systems
- drug discovery
- maximum likelihood estimation
- systems biology
- molecular interactions
- computational models
- three dimensional
- conjugate gradient
- maximum likelihood
- biologically inspired design
- complex biological systems
- linear regression
- missing data